Cell Cycle Checkpoints: Ensuring Proper Attachment of Sister Chromatids

Which cell cycle checkpoint ensures that sister chromatids are properly attached to spindle fibers and are positioned along the equatorial plate to be split correctly?

OM checkpoint OG 1 checkpoint OG2 checkpoint O prophase checkpoint

Answer:

The OG2 checkpoint ensures proper attachment of sister chromatids to spindle fibers in the cell cycle.

The cell cycle checkpoint that ensures that sister chromatids are properly attached to spindle fibers and positioned along the equatorial plate to be split correctly is the OG2 checkpoint. At this checkpoint, the cell checks for proper attachment of the chromosomes to the spindle fibers before proceeding to anaphase, where the sister chromatids are separated. If the attachment is not correct, the cell cycle is paused to allow time for correction. Only when the attachments are proper, the cell proceeds to complete the cell division process.

It is crucial for sister chromatids to be correctly attached to spindle fibers during cell division to prevent errors in chromosome segregation. The OG2 checkpoint plays a key role in ensuring the accuracy of this process, ultimately contributing to the fidelity of cell division.

Overall, understanding the role of cell cycle checkpoints, such as the OG2 checkpoint, can provide valuable insights into the intricate mechanisms that govern the division of cells and the maintenance of genomic stability. By ensuring proper attachment of sister chromatids, cells can divide accurately and efficiently, contributing to overall cellular health and function.