Cluster of Differentiation (CD) Molecules: Key Players in Immune System Recognition

What are CD3, CD15, CD20, CD30, and CD45?

How do these molecules contribute to identifying and differentiating white blood cells?

CD3, CD15, CD20, CD30, and CD45 are known as Cluster of Differentiation (CD) molecules. What is their role?

These molecules are surface glycoproteins produced by all T cells and are used to identify and differentiate the various types of white blood cells or lymphocytes. They help in distinguishing between different types of immune cells.

The Cluster of Differentiation (CD) molecules, including CD3, CD15, CD20, CD30, and CD45, are essential surface markers that play a crucial role in the recognition and functioning of the immune system. These molecules are produced by T cells and aid in the identification and differentiation of various types of white blood cells or lymphocytes.

For example, CD3 is a co-receptor on T cells that contributes to T-cell activation and serves as a marker for T-cell development and lineage. CD15 is expressed on granulocytes and is involved in cell adhesion and migration. CD20 is found on B cells and plays a role in their activation. CD30 is a member of the tumor necrosis factor receptor superfamily and is expressed on activated T and B cells. CD45 is a common leukocyte antigen found on all white blood cells.

These CD molecules help in identifying and distinguishing between different subsets of immune cells, contributing to the overall functioning of the immune system. They aid in immune response modulation and play a crucial role in immune surveillance and defense against pathogens.