Understanding Chevrons and Amorphous Eosinophilic Band in Histology

What are chevrons and amorphous eosinophilic band in histology? What is their significance?

1. A histologic hallmark associated with eosinophils and their role

Answer:

Chevrons and amorphous eosinophilic band are histologic hallmarks associated with eosinophils, white blood cells that play a role in immune responses against protozoa and helminths and can indicate certain medical conditions when levels are high.

The histologic hallmark of chevrons and amorphous eosinophilic band is associated with eosinophils, a type of white blood cell that is part of the immune response. Eosinophils are granulocytes that have granules staining with an acidic dye known as eosin. They are typically 2-4 percent of the total leukocyte count and measure 10-12 µm in diameter.

These cells contain major basic protein and histamine within their granules. They facilitate responses particularly to protozoa and helminths, as they release antihistamines and are especially active against parasitic worms. High levels of eosinophils can indicate patients experiencing allergies, parasitic worm infestations, and some autoimmune diseases.