What is the Frequency of the NN Genotype Among 2,000 British Citizens?
Calculating the Frequency of the NN Genotype
The MN blood group phenotypes of 2,000 British citizens were 596M, 978MN, and 426N. We are tasked to determine the frequency of the NN genotype based on this data.
Options:
A. 0.106
B. 0.149
C. 0.457
D. 0.213
E. 0.915
Final answer:
The frequency of the NN genotype among 2,000 British citizens, based on the given MN blood group phenotypes, is 0.213.
Explanation:
The question asks about the frequency of the NN genotype in a sample of British citizens and their MN blood group phenotypes. Given the data of 2,000 individuals, where 596 show M phenotype, 978 show MN phenotype, and 426 show N phenotype, we can calculate the frequency of the NN genotype. To find this frequency, we look specifically at individuals with the N phenotype because only individuals homozygous for the N allele (NN genotype) will express this phenotype.
The NN genotype frequency is the number of individuals with the N phenotype divided by the total sample size. Therefore, frequency = 426 / 2000 = 0.213.
The correct answer to the question is D, which corresponds to a frequency of 0.213 for the NN genotype among the sampled British citizens.